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Amphotericin B derivative with reduced toxicity
Martin D Burke
(Inventor), Brice E Uno (Inventor)
University of Illinois Urbana-Champaign
Chemistry
Beckman Institute for Advanced Science and Technology
Biochemistry
Carl R. Woese Institute for Genomic Biology
Biomedical and Translational Sciences
Siebel Center for Design
Center for Global Studies
Research output
:
Patent
Overview
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Keyphrases
Reduced Toxicity
100%
Amphotericin B
100%
Parent Compounds
40%
Pharmaceutical Composition
40%
Human Cells
20%
Derivative Method
20%
Cholesterol
20%
Fungi
20%
Epimer
20%
Ergosterol
20%
Stereogenic Centers
20%
Therapeutic Index
20%
Fungal Infection
20%
Yeast Infection
20%
No Toxicity
20%
Pharmacology, Toxicology and Pharmaceutical Science
Amphotericin B Derivative
100%
Amphotericin B
66%
Therapeutic Window
33%
Mycosis
33%
Ergosterol
33%