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Amphotericin B derivative with reduced toxicity
Martin D Burke
(Inventor), Brice E Uno (Inventor)
University of Illinois Urbana-Champaign
Carle Illinois College of Medicine
Chemistry
Beckman Institute for Advanced Science and Technology
Biochemistry
Carl R. Woese Institute for Genomic Biology
Biomedical and Translational Sciences
Research output
:
Patent
Overview
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Keyphrases
Reduced Toxicity
100%
Amphotericin B
100%
Parent Compounds
40%
Pharmaceutical Composition
40%
Human Cells
20%
Derivative Method
20%
Cholesterol
20%
Fungi
20%
Epimer
20%
Ergosterol
20%
Stereogenic Centers
20%
Therapeutic Index
20%
Fungal Infection
20%
Yeast Infection
20%
No Toxicity
20%
Pharmacology, Toxicology and Pharmaceutical Science
Amphotericin B Derivative
100%
Amphotericin B
66%
Therapeutic Window
33%
Mycosis
33%
Ergosterol
33%