Ambulation and multiple sclerosis

Robert W. Motl

Research output: Contribution to journalReview articlepeer-review


Walking impairment is a common consequence of multiple sclerosis (MS) that can result in substantial limitations of daily activities and compromised quality of life. Walking impairment is often monitored as an indicator of disease and neurologic disability progression. The worsening of walking performance while undertaking a cognitive task underscores the role of nonmotor impairments in ambulation limitations. Walking impairment has ubiquitous and life-altering consequences, underscoring the importance of continued efforts to identify approaches to prevent and forestall this event, and to restore walking ability in persons with MS.

Original languageEnglish (US)
Pages (from-to)325-336
Number of pages12
JournalPhysical Medicine and Rehabilitation Clinics of North America
Issue number2
StatePublished - May 2013


  • Ambulation
  • Disability
  • Exercise
  • Multiple sclerosis
  • Quality of life
  • Walking

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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