Altered regulation of escherichia coli biotin biosynthesis in bira superrepressor mutant strains

Keyphrases

• Escherichia Coli 100%
• Mutant Strains 100%
• BirA 100%
• Biotin Biosynthesis 100%
• Biotin 61%
• Biotin Operon 30%
• Ligase 15%
• Derepression 15%
• Adenylates 15%
• Screening Approach 7%
• DNA Binding 7%
• Peptide Sequencing 7%
• Dimerization 7%
• Single-point mutation 7%
• Catalytic Domain 7%
• Purified Proteins 7%
• Dimer Interface 7%
• Mutant Protein 7%
• Overproduction 7%
• Ligation 7%
• Operator DNA 7%
• Transcriptional Repression 7%
• Lethal mutations 7%
• Regulatory System 7%
• Wild Strain 7%
• Multiple mutations 7%
• Ligation Reactions 7%
• Biotin Ligase 7%
• Electrophoretic Mobility Shift Assay 7%
• 5'-AMP 7%
• Combined Selection 7%

Biochemistry, Genetics and Molecular Biology

• Anabolism 100%
• Escherichia coli 100%
• Biotin 100%
• Operon 28%
• Transcription 28%
• Wild Type 21%
• Ligase 21%
• Adenosine Monophosphate 21%
• Dimerization 14%
• Enzyme 14%
• Allele 14%
• Derepression 14%
• DNA Binding 7%
• Peptide Sequence 7%
• Enzyme Active Site 7%
• Mutant Protein 7%
• Electrophoretic Mobility Shift Assay 7%
• Lethal Mutation 7%
• Type Strain 7%

Immunology and Microbiology

• Escherichia coli 100%
• Operon 100%
• Wild Type 75%
• Dimerization 50%
• Allele 50%
• Amino Acid Sequence 25%
• DNA Binding 25%
• Lethal Mutation 25%
• Type Strain 25%
• Enzyme Active Site 25%
• Gel Mobility Shift Assay 25%