All-optical microfluidic circuit for biochemical and cellular analysis powered by photoactive nanoparticles

Gang L. Liu, Jaeyoun Kim, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution


We have invented a novel all-optical-logic microfluidic system which is automatically controlled only by visible or near infrared light with down to submilliwatt power. No electric power supply, no external or MEMS pump, no tubings or connectors, no microfluidic valves, nor surface patterning are required in our system. Our device only consists of a single-layer PDMS microfluidic chip and newly invented photoactive nanoparticles. Our photoactive nanoparticles are capable of converting optical energy to hydrodynamic energy in fluids. The nanoparticle themselves are biocompatible and can be biofunctionalized. Via these photoactive nanoparticles, we used only light to drive, guide, switch and mix liquid in optofluidic logic circuits with desired speeds and directions. We demonstrated the optofluidic controls in transportation of biomolecules and cells.

Original languageEnglish (US)
Title of host publicationOptofluidics
StatePublished - 2006
EventOptofluidics - San Diego, CA, United States
Duration: Aug 15 2006Aug 16 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


Country/TerritoryUnited States
CitySan Diego, CA


  • All-optical
  • Microfluidics
  • Nanoparticles
  • Optofluidics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics


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