TY - JOUR
T1 - Age dependent changes in metallothionein and accumulation of cadmium in horses
AU - Jeffery, Elizabeth H.
AU - Noseworthy, R.
AU - Cherian, M. George
PY - 1989
Y1 - 1989
N2 - 1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.
AB - 1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.
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U2 - 10.1016/0742-8413(89)90242-9
DO - 10.1016/0742-8413(89)90242-9
M3 - Article
C2 - 2572387
AN - SCOPUS:0024432153
SN - 0306-4492
VL - 93
SP - 327
EP - 332
JO - Comparative Biochemistry and Physiology. Part C, Comparative
JF - Comparative Biochemistry and Physiology. Part C, Comparative
IS - 2
ER -