Age dependent changes in metallothionein and accumulation of cadmium in horses

Elizabeth H. Jeffery; R. Noseworthy; M. George Cherian

doi:10.1016/0742-8413(89)90242-9

Age dependent changes in metallothionein and accumulation of cadmium in horses

Elizabeth H. Jeffery, R. Noseworthy, M. George Cherian

Food Science and Human Nutrition

Research output: Contribution to journal › Article › peer-review

Abstract

1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.

Original language	English (US)
Pages (from-to)	327-332
Number of pages	6
Journal	Comparative Biochemistry and Physiology. Part C, Comparative
Volume	93
Issue number	2
DOIs	https://doi.org/10.1016/0742-8413(89)90242-9
State	Published - 1989

ASJC Scopus subject areas

Immunology
Pharmacology

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title = "Age dependent changes in metallothionein and accumulation of cadmium in horses",

abstract = "1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.",

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AU - Jeffery, Elizabeth H.

AU - Noseworthy, R.

AU - Cherian, M. George

PY - 1989

Y1 - 1989

N2 - 1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.

AB - 1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasm in liver and kidney of horses by immunohistochemistry.

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JO - Comparative biochemistry and physiology. C: Comparative pharmacology

JF - Comparative biochemistry and physiology. C: Comparative pharmacology

SN - 0306-4492

IS - 2

ER -

Age dependent changes in metallothionein and accumulation of cadmium in horses

Abstract

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