Young (3-5 months) and middle-aged (17-19 months) ovariectomized rats were treated with estradiol benzoate for three days and striatal dopaminergic function was assessed behaviorally (circling in response to apomorphine) and neurochemically (binding of [3H]spiroperiodoly striatal membranes). The results suggest that striatal dopaminergic function may respond differently to estrogen in older animals compared to younger animals.
|Original language||English (US)|
|Number of pages||3|
|Journal||European Journal of Pharmacology|
|State||Published - Aug 13 1982|
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