Age alters dopaminergic responses to estradiol

Edward J. Roy, Susan Sheinkop, Marlene A. Wilson

Research output: Contribution to journalArticle

Abstract

Young (3-5 months) and middle-aged (17-19 months) ovariectomized rats were treated with estradiol benzoate for three days and striatal dopaminergic function was assessed behaviorally (circling in response to apomorphine) and neurochemically (binding of [3H]spiroperiodoly striatal membranes). The results suggest that striatal dopaminergic function may respond differently to estrogen in older animals compared to younger animals.

Original languageEnglish (US)
Pages (from-to)73-75
Number of pages3
JournalEuropean Journal of Pharmacology
Volume82
Issue number1-2
DOIs
StatePublished - Aug 13 1982

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Keywords

  • Age
  • Dopamine
  • Estrogens

ASJC Scopus subject areas

  • Pharmacology

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