Aerobic exercise training and arterial changes in african americans versus caucasians

Sushant M. Ranadive, Huimin Yan, Abbi D. Lane, Rebecca M. Kappus, Marc D. Cook, Peng Sun, Idethia Harvey, Robert Ploutz-Synder, Jeffrey A Woods, Kenneth Wilund, Bo Fernhall

Research output: Contribution to journalArticle

Abstract

African Americans (AA) have increased carotid artery intima-media thickness and decreased vascular function compared with their Caucasian (CA) peers. Aerobic exercise prevents and potentially reverses arterial dysfunction. Purpose: The purpose of this study was to examine the effect of 8 wk of moderate-to high-intensity aerobic training in young healthy sedentary AA and CA men and women. Methods: Sixty-four healthy volunteers (men, 28; women, 36) with mean age 24 yr underwent measures of arterial structure, function, and blood pressure (BP) variables at baseline, after the 4-wk control period, and 8 wk after training. Results: There was a significant increase inV O2peak among both groups after exercise training. Brachial systolic BP decreased significantly after the control period in both groups but not after exercise training. Carotid pulse pressure decreased significantly in both groups after exercise training as comparedwith that in baseline. Therewas no change in any of the otherBP variables.AAhad higher intima-media thickness at baseline and after the control period but it significantly decreased after exercise training comparedwith that ofCA.AAhad significantly lower baseline forearm blood flow and reactive hyperemia compared with those of CA, but exercise training had no effect on these variables. There was no significant difference in arterial stiffness (central pulse wave velocity) and wave-reflection (augmentation index) between the two groups at any time point. Conclusions: This is the first study to show that 8 wk of aerobic exercise training causes significant improvement in the arterial structure in young, healthy AA, making it comparable with the CA and with minimal effects on BP variables.

Original languageEnglish (US)
Pages (from-to)90-97
Number of pages8
JournalMedicine and Science in Sports and Exercise
Volume48
Issue number1
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

African Americans
Exercise
Blood Pressure
Carotid Intima-Media Thickness
Pulse Wave Analysis
Vascular Stiffness
Hyperemia
Carotid Arteries
Forearm
Blood Vessels
Healthy Volunteers
Arm

Keywords

  • Arterial Function
  • Arterial Structure
  • Exercise Training
  • Intima-Media Thickness
  • Race And Ethnicity

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Ranadive, S. M., Yan, H., Lane, A. D., Kappus, R. M., Cook, M. D., Sun, P., ... Fernhall, B. (2016). Aerobic exercise training and arterial changes in african americans versus caucasians. Medicine and Science in Sports and Exercise, 48(1), 90-97. https://doi.org/10.1249/MSS.0000000000000742

Aerobic exercise training and arterial changes in african americans versus caucasians. / Ranadive, Sushant M.; Yan, Huimin; Lane, Abbi D.; Kappus, Rebecca M.; Cook, Marc D.; Sun, Peng; Harvey, Idethia; Ploutz-Synder, Robert; Woods, Jeffrey A; Wilund, Kenneth; Fernhall, Bo.

In: Medicine and Science in Sports and Exercise, Vol. 48, No. 1, 01.01.2016, p. 90-97.

Research output: Contribution to journalArticle

Ranadive, SM, Yan, H, Lane, AD, Kappus, RM, Cook, MD, Sun, P, Harvey, I, Ploutz-Synder, R, Woods, JA, Wilund, K & Fernhall, B 2016, 'Aerobic exercise training and arterial changes in african americans versus caucasians', Medicine and Science in Sports and Exercise, vol. 48, no. 1, pp. 90-97. https://doi.org/10.1249/MSS.0000000000000742
Ranadive, Sushant M. ; Yan, Huimin ; Lane, Abbi D. ; Kappus, Rebecca M. ; Cook, Marc D. ; Sun, Peng ; Harvey, Idethia ; Ploutz-Synder, Robert ; Woods, Jeffrey A ; Wilund, Kenneth ; Fernhall, Bo. / Aerobic exercise training and arterial changes in african americans versus caucasians. In: Medicine and Science in Sports and Exercise. 2016 ; Vol. 48, No. 1. pp. 90-97.
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