Advancing Exercise Science for Better Health Outcomes Across the Spectrum of Chronic Kidney Disease

Clara Bohm, Paul Bennett, Kelly Lambert, Ken Wilund, Nancy Verdin, Kevin Fowler, Keiichi Sumida, Angela Yee Moon Wang, Navdeep Tangri, Jennifer M. MacRae, Stephanie Thompson

Research output: Contribution to journalReview articlepeer-review


Despite over 30 years of evidence for improvements in physical function, physical fitness, and health-related quality of life with exercise training in individuals with chronic kidney disease, access to dedicated exercise training programs remains outside the realm of standard of care for most kidney care programs. In this review, we explore possible reasons for this by comparing approaches in other chronic diseases where exercise rehabilitation has become the standard of care, identifying enablers and factors that need to be addressed for continued growth in this area, and discussing knowledge gaps for future research. For exercise rehabilitation to be relevant to all stakeholders and become a sustainable component of kidney care, a focus on the effect of exercise on clinically relevant outcomes that are prioritized by individuals living with kidney disease, use of evidence-based implementation strategies for diverse settings and populations, and approaching exercise as a medical therapy are required.

Original languageEnglish (US)
Pages (from-to)S103-S109
JournalJournal of Renal Nutrition
Issue number6
StatePublished - Nov 2023


  • chronic kidney disease
  • dialysis
  • exercise rehabilitation
  • medical therapy
  • physical activity
  • review

ASJC Scopus subject areas

  • Nephrology
  • Nutrition and Dietetics
  • Medicine (miscellaneous)


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