Advances in Pulsed Doppler Methods for Peripheral Perfusion Imaging

Michael F. Insana, Yang Zhu, Min Woo Kim, L. Wawrzyniec Dobrucki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report on methods for imaging blood perfusion in peripheral skeletal muscle tissues without exogenous contrast enhancement. The ultimate goal is to provide new tools for monitoring the development and treatment of peripheral artery disease (PAD) in diabetic patients. Sparse ultrasonic pulse-echo acquisitions are arranged into 3-D echo data arrays. Each array is decomposed using higher-order singular value decomposition (HOSVD) methods to uncouple echo sources for clutter filtering before signal power is mapped into power Doppler (PD) images. This method enables further segmentation of the blood-echo power into flow maps covering non-overlapping velocity ranges. Our method is compared with other imaging modalities that together assess the recovery in a murine hindlimb ischemia model of PAD.

Original languageEnglish (US)
Title of host publication2019 IEEE International Ultrasonics Symposium, IUS 2019
PublisherIEEE Computer Society
Pages1164-1168
Number of pages5
ISBN (Electronic)9781728145969
DOIs
StatePublished - Oct 2019
Event2019 IEEE International Ultrasonics Symposium, IUS 2019 - Glasgow, United Kingdom
Duration: Oct 6 2019Oct 9 2019

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2019-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2019 IEEE International Ultrasonics Symposium, IUS 2019
CountryUnited Kingdom
CityGlasgow
Period10/6/1910/9/19

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Keywords

  • SVD clutter filtering
  • ischemic tissue assessment
  • label-free imaging
  • pulse sampling
  • tumor blood flow

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Insana, M. F., Zhu, Y., Kim, M. W., & Dobrucki, L. W. (2019). Advances in Pulsed Doppler Methods for Peripheral Perfusion Imaging. In 2019 IEEE International Ultrasonics Symposium, IUS 2019 (pp. 1164-1168). [8925694] (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2019.8925694