Advances in phylogeny reconstruction from gene order and content data

Bernard M.E. Moret, Tandy Warnow

Research output: Contribution to journalArticlepeer-review


Genomes can be viewed in terms of their gene content and the order in which the genes appear along each chromosome. Evolutionary events that affect the gene order or content are "rare genomic events" (rarer than events that affect the composition of the nucleotide sequences) and have been advocated by systematists for inferring deep evolutionary histories. This chapter surveys recent developments in the reconstruction of phylogenies from gene order and content, focusing on their performance under various stochastic models of evolution. Because such methods are quite restricted in the type of data they can analyze, we also present research aimed at handling the full range of whole-genome data.

Original languageEnglish (US)
Pages (from-to)673-700
Number of pages28
JournalMethods in enzymology
StatePublished - 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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