TY - GEN
T1 - Advances in Electronic Nano-biosensors and New Frontiers in Bioengineering
AU - Chen, Sihan
AU - Hwang, Michael T.
AU - Wang, Jiaojiao
AU - Ganguli, Anurup
AU - Park, Insu
AU - Kim, Yongdeok
AU - Valera, Enrique
AU - Nam, Sung Woo
AU - Aluru, Narayana R.
AU - Van Der Zande, Arend M.
AU - Bashir, Rashid
N1 - Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - Nano-biosensors offer unprecedented sensitivities over conventional biosensors and enable single bio-molecule analysis. Electronic nano-biosensors offer advantages of label-free detection, low cost, and potential for high-density parallelization. In this paper, we review our past work on electrical detection of DNA and proteins on silicon field-effect transistor (FET) biosensors, ultrasensitive detection of DNA, proteins, and viruses using crumpled graphene FETs, and solid-state nanopore devices for characterization of individual DNA molecules. In addition, a new frontier in bioengineering is the use of biological components for applications in engineering and computing. We also highlight our work on muscle-based miniature bio-robots, and briefly discuss our ongoing work on developing neuron-based bio-computers.
AB - Nano-biosensors offer unprecedented sensitivities over conventional biosensors and enable single bio-molecule analysis. Electronic nano-biosensors offer advantages of label-free detection, low cost, and potential for high-density parallelization. In this paper, we review our past work on electrical detection of DNA and proteins on silicon field-effect transistor (FET) biosensors, ultrasensitive detection of DNA, proteins, and viruses using crumpled graphene FETs, and solid-state nanopore devices for characterization of individual DNA molecules. In addition, a new frontier in bioengineering is the use of biological components for applications in engineering and computing. We also highlight our work on muscle-based miniature bio-robots, and briefly discuss our ongoing work on developing neuron-based bio-computers.
UR - http://www.scopus.com/inward/record.url?scp=85147512041&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85147512041&partnerID=8YFLogxK
U2 - 10.1109/IEDM45625.2022.10019512
DO - 10.1109/IEDM45625.2022.10019512
M3 - Conference contribution
AN - SCOPUS:85147512041
T3 - Technical Digest - International Electron Devices Meeting, IEDM
SP - 1711
EP - 1714
BT - 2022 International Electron Devices Meeting, IEDM 2022
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2022 International Electron Devices Meeting, IEDM 2022
Y2 - 3 December 2022 through 7 December 2022
ER -