TY - GEN
T1 - Advances in contrast enhancement for optical coherence tomography
AU - Boppart, Stephen A.
PY - 2006
Y1 - 2006
N2 - Contrast in optical coherence tomography (OCT) images is often limited, particularly when pathological tissue is morphologically or optically similar to normal tissue. In recent years, there has been increasing interest in developing methods for enhancing OCT contrast. In general, contrast can be enhanced by the administration of passive or targeted exogenous contrast agents, or by exploiting linear and nonlinear techniques for sampling the endogenous molecular composition of tissue. Many exogenous agents, in addition to being targeted to specific cells and tissues, can also serve as multifunctional agents, delivering or facilitating therapy as well as providing enhanced contrast for imaging and localization. This paper and presentation will discuss novel OCT contrast enhancing methods designed to selectively identify tissues of interest.
AB - Contrast in optical coherence tomography (OCT) images is often limited, particularly when pathological tissue is morphologically or optically similar to normal tissue. In recent years, there has been increasing interest in developing methods for enhancing OCT contrast. In general, contrast can be enhanced by the administration of passive or targeted exogenous contrast agents, or by exploiting linear and nonlinear techniques for sampling the endogenous molecular composition of tissue. Many exogenous agents, in addition to being targeted to specific cells and tissues, can also serve as multifunctional agents, delivering or facilitating therapy as well as providing enhanced contrast for imaging and localization. This paper and presentation will discuss novel OCT contrast enhancing methods designed to selectively identify tissues of interest.
UR - http://www.scopus.com/inward/record.url?scp=34047170936&partnerID=8YFLogxK
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U2 - 10.1109/IEMBS.2006.259366
DO - 10.1109/IEMBS.2006.259366
M3 - Conference contribution
C2 - 17946382
AN - SCOPUS:34047170936
SN - 1424400325
SN - 9781424400324
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 121
EP - 124
BT - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
T2 - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Y2 - 30 August 2006 through 3 September 2006
ER -