Advances in contrast agents, reporters, and detection

The combination of biological principles, quantitative imaging techniques, and optical probes (reporters) is expected to lead to improved tools to monitor molecular level tissue transformation and disease-associated processes and to improve clinical outcomes. In view of this, the need for contrast agents is becoming very important. The challenge now is that whether molecular biopsy will deliver its promise of low-toxicity, long-term stability, spectroscopic properties, and as a human clinical tool.