Advances in contrast agents, reporters, and detection

D. J. Bornhop, C. H. Contag, K. Licha, C. J. Murphy

Research output: Contribution to journalArticlepeer-review


The combination of biological principles, quantitative imaging techniques, and optical probes (reporters) is expected to lead to improved tools to monitor molecular level tissue transformation and disease-associated processes and to improve clinical outcomes. In view of this, the need for contrast agents is becoming very important. The challenge now is that whether molecular biopsy will deliver its promise of low-toxicity, long-term stability, spectroscopic properties, and as a human clinical tool.

Original languageEnglish (US)
Pages (from-to)106-110
Number of pages5
JournalJournal of biomedical optics
Issue number2
StatePublished - Apr 2001
Externally publishedYes


  • Contrast agents
  • Detection
  • Reporters

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Atomic and Molecular Physics, and Optics
  • Radiological and Ultrasound Technology


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