@inproceedings{46d8636239ef410ba347c87c6d816e2c,
title = "Advanced laser system for 3D optoacoustic tomography of the breast",
abstract = "We describe the ongoing development and performance of a high-pulse-energy wavelength-cycling laser system for three-dimensional optoacoustic tomography of the breast. Joule-level energies are desired for achieving the required penetration depths while maintaining safe fluence levels. Wavelength cycling provides a pulse sequence which repeatedly alternates between two wavelengths (approximately 756 and 797 nm) that provide differential imaging. This improves co-registration of captured differential images and quantification of blood oxygen saturation. New design features have been developed for and incorporated into a clinical prototype laser system, to improve efficacy and ease of use in the clinic. We describe the benefits of these features for operation with a clinical pilot optoacoustic/ultrasound dual-modality three-dimensional imaging system.",
keywords = "alexandrite laser, breast cancer, mammography, Optoacoustic imaging, photoacoustic imaging, pulsed laser, tomography, tumor",
author = "Marc Klosner and Gary Chan and Chunbai Wu and Heller, {Donald F.} and Richard Su and Sergey Ermilov and Brecht, {Hans Peter} and Vassili Ivanov and Pratik Talole and Yang Lou and Mark Anastasio and Alexander Oraevsky",
note = "Funding Information: This work was supported in part by National Institutes of Health/National Institute of Biomedical Imaging and Biomedical Engineering SBIR Phase I Grant 1R43EB016479-01A1 and National Institutes of Health/National Cancer Institute Grant R01CA167446. Publisher Copyright: {\textcopyright} 2016 SPIE.; Photons Plus Ultrasound: Imaging and Sensing 2016 ; Conference date: 14-02-2016 Through 17-02-2016",
year = "2016",
month = jan,
day = "1",
doi = "10.1117/12.2209398",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Oraevsky, {Alexander A.} and Wang, {Lihong V.}",
booktitle = "Photons Plus Ultrasound",
address = "United States",
}