Laminated safety glass samples with different levels of adhesive bond strength were manufactured and tested using mechanical guided waves. The results were then compared with those obtained using the commonly used destructive testing method, i.e., the pummel test method. The imperfect interfaces between the plastic interlayer and the two adjacent glass plates were modeled using a bed of longitudinal and shear springs. The spring constants were estimated using fracture mechanics concepts in conjunction with surface analysis using atomic force microscopy. The guided wave theoretical attenuation-based predictions of adhesion levels (obtained using this multilayered model) were validated using experimental attenuation measurements. Results show that this approach is useful in the nondestructive assessment of adhesive bond strength in laminated safety glass.