Acute liver failure: An uncommon complication of commonly used medication

Muhammad Z. Bawany; Burhan Bhutto; Wael I. Youssef; Ali Nawras; Thomas Sodeman

doi:10.1097/MJT.0b013e3182192d5a

Acute liver failure: An uncommon complication of commonly used medication

Muhammad Z. Bawany, Burhan Bhutto, Wael I. Youssef, Ali Nawras, Thomas Sodeman

Research output: Contribution to journal › Article › peer-review

Abstract

The incidence of drug-related acute liver failure is approximately 14 per 100,000 populations. Druginduced liver injury may take place through a variety of mechanism. Withdrawal of the offending agent may result in complete recovery. Clindamycin is known to cause mild derangement of liver function; however, acute liver injury causing severe derangement of liver function associated with encephalopathy is uncommon.

Original language	English (US)
Pages (from-to)	566-568
Number of pages	3
Journal	American Journal of Therapeutics
Volume	20
Issue number	5
DOIs	https://doi.org/10.1097/MJT.0b013e3182192d5a
State	Published - Sep 2013
Externally published	Yes

Keywords

Acute liver injury
Drug-induced liver injury
Hepatitis

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

Online availability

10.1097/MJT.0b013e3182192d5a

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abstract = "The incidence of drug-related acute liver failure is approximately 14 per 100,000 populations. Druginduced liver injury may take place through a variety of mechanism. Withdrawal of the offending agent may result in complete recovery. Clindamycin is known to cause mild derangement of liver function; however, acute liver injury causing severe derangement of liver function associated with encephalopathy is uncommon.",

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AU - Bhutto, Burhan

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AU - Sodeman, Thomas

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AB - The incidence of drug-related acute liver failure is approximately 14 per 100,000 populations. Druginduced liver injury may take place through a variety of mechanism. Withdrawal of the offending agent may result in complete recovery. Clindamycin is known to cause mild derangement of liver function; however, acute liver injury causing severe derangement of liver function associated with encephalopathy is uncommon.

KW - Acute liver injury

KW - Drug-induced liver injury

KW - Hepatitis

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ER -

Acute liver failure: An uncommon complication of commonly used medication

Abstract

Keywords

ASJC Scopus subject areas

Online availability

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