Active-Site Mutations of Diphtheria Toxin: Role of Tyrosine-65 in NAD Binding and ADP-Ribosylation

Keyphrases

• Active Site mutant 100%
• Active Sites 25%
• Adenosine 25%
• ADP-ribosylation 100%
• Diphtheria Toxin 100%
• Direct Displacement 25%
• Displacement Mechanism 25%
• Dissociation Constant 25%
• Elongation Factor 2 25%
• Mutant Enzyme 25%
• N-glycosidic Bond 25%
• NAD Glycohydrolase 25%
• Nicotinamide 25%
• Nucleophile 25%
• Phenylalanine 75%
• Site-directed mutagenesis 25%
• Synthetic Gene 25%
• Tyrosine 100%

Immunology and Microbiology

• Adenosine Diphosphate Ribosylation 100%
• Dissociation Constant 25%
• Elongation Factor 2 25%
• Site Directed Mutagenesis 25%
• Wild Type 50%