Activation of 2-aminofluorene by cultured plant cells

Michael J. Plewa, Danny L. Weaver, L. Curt Blair, James M. Gentile

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Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2- aminofluorene is heat-inactivated and may not involve solely cytochrome P450. The kinetics of activation demonstrated both time- and concentration-dependent responses.

Original languageEnglish (US)
Pages (from-to)1427-1429
Number of pages3
Issue number4591
StatePublished - 1983

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    Plewa, M. J., Weaver, D. L., Blair, L. C., & Gentile, J. M. (1983). Activation of 2-aminofluorene by cultured plant cells. Science, 219(4591), 1427-1429.