Activation of 2-aminofluorene by cultured plant cells

Michael J. Plewa; Danny L. Weaver; L. Curt Blair; James M. Gentile

doi:10.1126/science.6338591

Activation of 2-aminofluorene by cultured plant cells

Michael J. Plewa, Danny L. Weaver, L. Curt Blair, James M. Gentile

Crop Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2- aminofluorene is heat-inactivated and may not involve solely cytochrome P450. The kinetics of activation demonstrated both time- and concentration-dependent responses.

Original language	English (US)
Pages (from-to)	1427-1429
Number of pages	3
Journal	Science
Volume	219
Issue number	4591
DOIs	https://doi.org/10.1126/science.6338591
State	Published - 1983

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@article{c96b6852d067417cb56dfee55a7a8214,

title = "Activation of 2-aminofluorene by cultured plant cells",

abstract = "Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2- aminofluorene is heat-inactivated and may not involve solely cytochrome P450. The kinetics of activation demonstrated both time- and concentration-dependent responses.",

author = "Plewa, {Michael J.} and Weaver, {Danny L.} and Blair, {L. Curt} and Gentile, {James M.}",

year = "1983",

doi = "10.1126/science.6338591",

language = "English (US)",

volume = "219",

pages = "1427--1429",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4591",

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TY - JOUR

T1 - Activation of 2-aminofluorene by cultured plant cells

AU - Plewa, Michael J.

AU - Weaver, Danny L.

AU - Blair, L. Curt

AU - Gentile, James M.

PY - 1983

Y1 - 1983

N2 - Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2- aminofluorene is heat-inactivated and may not involve solely cytochrome P450. The kinetics of activation demonstrated both time- and concentration-dependent responses.

AB - Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2- aminofluorene is heat-inactivated and may not involve solely cytochrome P450. The kinetics of activation demonstrated both time- and concentration-dependent responses.

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U2 - 10.1126/science.6338591

DO - 10.1126/science.6338591

M3 - Article

C2 - 6338591

AN - SCOPUS:0020631272

VL - 219

SP - 1427

EP - 1429

JO - Science

JF - Science

SN - 0036-8075

IS - 4591

ER -

Activation of 2-aminofluorene by cultured plant cells

Abstract

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