Activation and deactivation of Cp*Ir(TsDPEN) hydrogenation catalysts in water

Christopher S. Letko, Zachariah M. Heiden, Thomas B. Rauchfuss

Research output: Contribution to journalArticlepeer-review


The addition of H3PO4 to Cp*Ir(TsDPEN-H), where TsDPEN = H2NCHPhCHPhNTs, is a simple method to obtain a water-soluble hydrogenation catalyst capable of reducing aromatic ketones to their corresponding alcohols in aqueous solutions. Key to the reactivity is the low affinity of the coordinatively unsaturated [Cp*Ir(TsDPEN)]+ for H2PO4. Catalyst degradation proceeds via the protonation of the tosylamido ligand, as was established by the crystallographic characterization of the tosylamine complex [Cp*Ir(NCMe)(HTsDPEN)] 2+.

Original languageEnglish (US)
Pages (from-to)4927-4930
Number of pages4
JournalEuropean Journal of Inorganic Chemistry
Issue number33
StatePublished - 2009


  • Aqueous catalysis
  • Catalyst degradation
  • Homogeneous catalysis
  • Hydrides
  • Hydrogenation

ASJC Scopus subject areas

  • Inorganic Chemistry


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