Achievements, challenges, and future perspectives of epidemiologic research in restless legs syndrome (RLS)

Daniel L. Picchietti, Stephen K. Van Den Eeden, Yuichi Inoue, Klaus Berger

Research output: Contribution to journalReview articlepeer-review

Abstract

In the 20 years since the initial consensus on a common definition for restless legs syndrome (RLS), over 600 scientific reports on epidemiological aspects of RLS have been published. Most are descriptive and address important issues such as prevalence, familial patterns, comorbidities, and quality of life. While the establishment of prospective cohort studies and the use of secondary data sources are rather new to RLS research, both options significantly broaden the possibilities for analysis of disease risk factors. These two options, as well as the inclusion of a broader phenotyping of individual patients, have great potential to elucidate etiologic factors for RLS and expand knowledge about this common disorder. This article summarizes achievements in the area of RLS epidemiology, describes current challenges, and highlights future perspectives in the field.

Original languageEnglish (US)
Pages (from-to)3-9
Number of pages7
JournalSleep Medicine
Volume31
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Keywords

  • Epidemiology
  • Research methods
  • Restless legs syndrome
  • Secondary data analysis
  • Study design

ASJC Scopus subject areas

  • Medicine(all)

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