TY - JOUR
T1 - Acetate enhances solvent production and prevents degeneration in Clostridium beijerinckii BA101
AU - Chen, C. K.
AU - Blaschek, H. P.
N1 - Funding Information:
Acknowledgements This work was supported in part by the Illinois Corn Marketing Board and the U.S.D.A. National Research Initiative Value-Added Program (AG 96-35500-3247).
PY - 1999
Y1 - 1999
N2 - Addition of sodium acetate to chemically defined MP2 medium was found to increase and stabilize solvent production by Clostridium beijerinckii BA101, a solvent-hyperproducing mutant derived from C. beijerinckii NCIMB 8052. C. beijerinckii BA101 demonstrated a greater increase in solvent production than C. beijerinckii NCIMB 8052 when sodium acetate was added to MP2 medium. In 1- 1 batch fermentations, C. beijerinckii BA101 produced 32.6 g/1 total solvents, with butanol at 20.9 g/l, when grown in MP2 medium containing 60 mM sodium acetate and 8% glucose. To our knowledge, these values represent the highest solvent and butanol concentrations produced by a solventogenic Clostridium strain when grown in batch culture.
AB - Addition of sodium acetate to chemically defined MP2 medium was found to increase and stabilize solvent production by Clostridium beijerinckii BA101, a solvent-hyperproducing mutant derived from C. beijerinckii NCIMB 8052. C. beijerinckii BA101 demonstrated a greater increase in solvent production than C. beijerinckii NCIMB 8052 when sodium acetate was added to MP2 medium. In 1- 1 batch fermentations, C. beijerinckii BA101 produced 32.6 g/1 total solvents, with butanol at 20.9 g/l, when grown in MP2 medium containing 60 mM sodium acetate and 8% glucose. To our knowledge, these values represent the highest solvent and butanol concentrations produced by a solventogenic Clostridium strain when grown in batch culture.
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U2 - 10.1007/s002530051504
DO - 10.1007/s002530051504
M3 - Article
C2 - 10499256
AN - SCOPUS:0032868399
SN - 0175-7598
VL - 52
SP - 170
EP - 173
JO - Applied Microbiology and Biotechnology
JF - Applied Microbiology and Biotechnology
IS - 2
ER -