TY - JOUR
T1 - Accurate prediction of cardiorespiratory fitness using cycle ergometry in minimally disabled persons with relapsing-remitting multiple sclerosis
AU - Motl, Robert W.
AU - Fernhall, Bo
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2012/3
Y1 - 2012/3
N2 - Objective: To examine the accuracy of predicting peak oxygen consumption (VO2peak) primarily from peak work rate (WRpeak) recorded during a maximal, incremental exercise test on a cycle ergometer among persons with relapsing-remitting multiple sclerosis (RRMS) who had minimal disability. Design: Cross-sectional study. Setting: Clinical research laboratory. Participants: Women with RRMS (n=32) and sex-, age-, height-, and weight-matched healthy controls (n=16) completed an incremental exercise test on a cycle ergometer to volitional termination. Intervention: Not applicable. Main Outcome Measures: Measured and predicted VO2peak and WRpeak. Results: There were strong, statistically significant associations between measured and predicted VO2peak in the overall sample (R 2=.89, standard error of the estimate=127.4mL/min) and subsamples with (R2=.89, standard error of the estimate=131.3mL/ min) and without (R2=.85, standard error of the estimate= 126.8mL/min) multiple sclerosis (MS) based on the linear regression analyses. Based on the 95% confidence limits for worst-case errors, the equation predicted VO 2peak within 10% of its true value in 95 of every 100 subjects with MS. Conclusions: Peak VO2 can be accurately predicted in persons with RRMS who have minimal disability as it is in controls by using established equations and WRpeak recorded from a maximal, incremental exercise test on a cycle ergometer.
AB - Objective: To examine the accuracy of predicting peak oxygen consumption (VO2peak) primarily from peak work rate (WRpeak) recorded during a maximal, incremental exercise test on a cycle ergometer among persons with relapsing-remitting multiple sclerosis (RRMS) who had minimal disability. Design: Cross-sectional study. Setting: Clinical research laboratory. Participants: Women with RRMS (n=32) and sex-, age-, height-, and weight-matched healthy controls (n=16) completed an incremental exercise test on a cycle ergometer to volitional termination. Intervention: Not applicable. Main Outcome Measures: Measured and predicted VO2peak and WRpeak. Results: There were strong, statistically significant associations between measured and predicted VO2peak in the overall sample (R 2=.89, standard error of the estimate=127.4mL/min) and subsamples with (R2=.89, standard error of the estimate=131.3mL/ min) and without (R2=.85, standard error of the estimate= 126.8mL/min) multiple sclerosis (MS) based on the linear regression analyses. Based on the 95% confidence limits for worst-case errors, the equation predicted VO 2peak within 10% of its true value in 95 of every 100 subjects with MS. Conclusions: Peak VO2 can be accurately predicted in persons with RRMS who have minimal disability as it is in controls by using established equations and WRpeak recorded from a maximal, incremental exercise test on a cycle ergometer.
KW - Multiple sclerosis
KW - Physical fitness
KW - Rehabilitation
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U2 - 10.1016/j.apmr.2011.08.025
DO - 10.1016/j.apmr.2011.08.025
M3 - Article
C2 - 22225573
AN - SCOPUS:84859988892
SN - 0003-9993
VL - 93
SP - 490
EP - 495
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 3
ER -