A vinylsilane route to trans-7a-methylhydrind-4-en-1,6-dione

Scott E. Denmark, Juris P. Germanas

Research output: Contribution to journalArticlepeer-review


A stereoselective synthesis of the title compound is described. The overall yield is 34% starting with 2-methyl-2-cyclopentenone. The trans ring-fusion stereochemistry is established by a conjugate addition/trapping sequence.

Original languageEnglish (US)
Pages (from-to)1231-1234
Number of pages4
JournalTetrahedron Letters
Issue number12
StatePublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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