A simple and general platform for generating stereochemically complex polyene frameworks by iterative cross-coupling

Suk Joong Lee, Thomas M. Anderson, Martin D. Burke

Research output: Contribution to journalArticle

Abstract

Not so complex: A novel iterative cross-coupling strategy provides access to useful building blocks that enable the simple preparation of complex polyene natural-product motifs in all possible stereoisomeric forms. The method was used to synthesize the polyene core of vacidin A (see structure).

Original languageEnglish (US)
Pages (from-to)8860-8863
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number47
DOIs
StatePublished - Nov 15 2010

Keywords

  • MIDA boronates
  • haloboronic acids
  • iterative cross-coupling
  • polyenes
  • vacidin A

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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