@inproceedings{da4760bd7d8842f48cd3ef23e85db772,
title = "A silicon nanopore device for on-chip patch clamp measurements of single ion channel activity",
abstract = "Here we present a novel silicon nanopore planar patch clamp chip for single ion channel screening. We fabricate our devices using a combination of KOH and metal-assisted etching. Electrical characterization shows that the shunt capacitance and access resistance are within the accepted ranges for single channel recordings. In order to test our devices, we cultured and differentiated human neuroblastoma SH-SY5 Y cells on chip. We reliably obtained a high resistance seal to the cell membrane and report single ion channel activity recordings.",
author = "L. Plucinski and Y. Chen and Liu, {G. L.}",
note = "Publisher Copyright: {\textcopyright} 2014 Materials Research Society.; 2014 MRS Fall Meeting ; Conference date: 30-11-2014 Through 05-12-2014",
year = "2015",
doi = "10.1557/opl.2015.36",
language = "English (US)",
series = "Materials Research Society Symposium Proceedings",
publisher = "Materials Research Society",
pages = "29--32",
editor = "L. Liu and E. Park and H. Schmidt and X. Fan",
booktitle = "Materials and Concepts for Biomedical Sensing",
}