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A scalable approach to combinatorial library design for drug discovery
Puneet Sharma
,
Srinivasa Salapaka
,
Carolyn Beck
Mechanical Science and Engineering
Industrial and Enterprise Systems Engineering
Coordinated Science Lab
Information Trust Institute
Electrical and Computer Engineering
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Keyphrases
Annealing Algorithm
50%
Combinatorial Drugs
50%
Combinatorial Library Design
100%
Computational Effort
50%
Computationally Efficient
100%
Design Problems
50%
Deterministic Annealing
50%
Drug Discovery
100%
Experimental Resources
50%
Generation Design
50%
Large Classes
50%
Lead Generation
100%
Scalable Algorithms
50%
Scalable Approaches
100%
Truncation
50%
Computer Science
Computational Effort
100%
Design Problem
100%
Deterministic Annealing
100%
Identify Cluster
100%
Presented Framework
100%
Representativeness
100%