A regularized approach for freehand ultrasound elastography of breast lesions

Claire Pellot-Barakat, Frédérique Frouin, Alain Herment, Jerome J. Mai, Karen K. Lindfors, Jean K. Tsou, Patrick Von Behren, Michael F. Insana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We are developing a technique for freehand ultrasound elastography of breast lesions based on estimation of tissue deformation using Bayesian regularization. Displacements fields between RF fields acquired at rest and compressed states are estimated by minimizing a cost function consisting of echo amplitude conservation constraints and roughness penalty. Adaptations of a multi-scale deterministic optimization algorithm have been made to take into account the specific nature of RF data and improve and accelerate the convergence. Performances evaluated on gelatin phantoms demonstrate up to an order of magnitude reduction in image noise compared to conventionally used cross-correlation techniques without deterioration of contrast and resolution. Qualitative improvements are illustrated with a sequence acquired in vivo from a patient with fibrocystic changes and radial scars.

Original languageEnglish (US)
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages952-955
Number of pages4
ISBN (Print)0780383885, 9780780383883
StatePublished - 2004
Externally publishedYes
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume1

Other

Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/TerritoryUnited States
CityArlington, VA
Period4/15/044/18/04

ASJC Scopus subject areas

  • General Engineering

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