A probe design for the acquisition of homonuclear, heteronuclear, and inverse detected NMR spectra from multiple samples

X. Zhang, J. V. Sweedler, A. G. Webb

Research output: Contribution to journalEditorialpeer-review

Abstract

A new probe design is presented for obtaining homonuclear, heteronuclear, and inverse detected NMR spectra from more than one sample in the same total data acquisition time as for a single sample, thus increasing data acquisition efficiency. Specifically, a two-coil system, with each solenoidal coil impedance matched to 50 Ω at both proton and nitrogen frequencies, has been designed for operation at 11.7 T with an observe volume of 15 μL for each coil. Isolation between the two frequencies for each individual coil, and at each frequency between coils, was greater than 30 dB. Two-dimensional COSY and HMQC spectra were obtained with negligible NMR cross-talk between the two coils.

Original languageEnglish (US)
Pages (from-to)254-258
Number of pages5
JournalJournal of Magnetic Resonance
Volume153
Issue number2
DOIs
StatePublished - 2001

Keywords

  • Electrical decoupling
  • High throughput
  • HMQC spectroscopy
  • Parallel data acquisition
  • Solenoidal coils

ASJC Scopus subject areas

  • Molecular Biology
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

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