A partial-dithering strategy for edge-illumination X-ray phase-contrast tomography enabled by a joint reconstruction method

Yujia Chen, Charlotte K. Hagen, Alessandro Olivo, Mark A. Anastasio

Research output: Contribution to journalArticlepeer-review

Abstract

Edge-illumination X-ray phase-contrast tomography (EIXPCT) is a promising imaging technology where partially opaque masks are utilized with laboratory-based X-ray sources to estimate the distribution of the complex-valued refractive index. EIXPCT resolution is mainly determined by the period of a sample mask, but can be significantly improved by a dithering technique. Here, dithering means that multiple images per tomographic view angle are acquired as the object is moved over sub-pixel distances. Drawbacks of dithering include increased data-acquisition times and radiation doses. Motivated by the flexibility in data-acquisition designs enabled by a recently developed joint reconstruction method, a novel partial-dithering strategy for EIXPCT data-acquisition is proposed. In this strategy, dithering is implemented at only a subset of the tomographic view angles. The strategy can result in spatial resolution comparable to that of the conventional full-dithering strategy, where dithering is performed at every view angle, but the acquisition time is substantially decreased. Here, the effect of dithering parameters on image resolution is explored.

Original languageEnglish (US)
Article number105007
JournalPhysics in medicine and biology
Volume65
Issue number10
DOIs
StatePublished - May 21 2020

Keywords

  • data-acquisition
  • joint reconstruction
  • phase-contrast tomography

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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