@article{c27e487f47a74e858b043eaee5c6a782,
title = "A paleogenome from a Holocene individual supports genetic continuity in Southeast Alaska",
abstract = "Many specifics of the population histories of the Indigenous peoples of North America remain contentious owing to a dearth of physical evidence. Only few ancient human genomes have been recovered from the Pacific Northwest Coast, a region increasingly supported as a coastal migration route for the initial peopling of the Americas. Here, we report paleogenomic data from the remains of a ∼3,000-year-old female individual from Southeast Alaska, named Tat{\'o}ok y{\'i}k y{\'e}es sh{\'a}awat (TYYS). Our results demonstrate at least 3,000 years of matrilineal genetic continuity in Southeast Alaska, and that TYYS is most closely related to ancient and present-day northern Pacific Northwest Coast Indigenous Americans. We find no evidence of Paleo-Inuit (represented by Saqqaq) ancestry in present-day or ancient Pacific Northwest peoples. Instead, our analyses suggest the Saqqaq genome harbors Northern Native American ancestry. This study sheds further light on the human population history of the northern Pacific Northwest Coast.",
keywords = "Genomics, Human Genetics, Paleobiology",
author = "Alber Aqil and Stephanie Gill and Omer Gokcumen and Malhi, {Ripan S.} and Reese, {Esther Aalts{\'e}en} and Smith, {Jane L.} and Heaton, {Timothy T.} and Charlotte Lindqvist",
note = "The authors are particularly grateful to the Wrangell Cooperative Association for their support of this project. The authors also thank Tongass National Forest archaeologists Gina Esposito and Tiffany Brunson, soil scientist Jackie de-Montigny, University of South Dakota student field assistants Frank Andy Klock, Nathan Carter, Brandon Silver, Louis Rezac, Clarissa Ford, Alex Santos and Christy Heaton. The authors are thankful to Flavio da Silva Coelho for help with radiocarbon dating calibrations, Victor A. Albert for valuable comments on the manuscript, and Dilek Koptekin for insightful discussions during the review process. This research was supported with funding from the National Science Foundation (grant nos. 1556565, 1854550, 9870343, and 0208247) and the National Geographic Society (grant no. 6212-98). C.L. designed the study; S.G. extracted the DNA and performed initial analyses; A.A. and C.L. analyzed the data; R.S.M. provided data; E.A.R. organized collaborative opportunities between the Wrangell Cooperative Association, the USFS and C.L. for culturally-appropriate review of data, tribal examination of the site and naming of Tat{\'o}ok y{\'i}k y{\'e}es sh{\'a}awat; T.H.H. and J.S. performed the cave explorations and provided the sample and paleontological context; A.A. O.G. and C.L. wrote the manuscript with contributions from all authors. The authors declare no competing interests. We support inclusive, diverse, and equitable conduct of research. The authors are particularly grateful to the Wrangell Cooperative Association for their support of this project. The authors also thank Tongass National Forest archaeologists Gina Esposito and Tiffany Brunson, soil scientist Jackie de-Montigny, University of South Dakota student field assistants Frank Andy Klock, Nathan Carter, Brandon Silver, Louis Rezac, Clarissa Ford, Alex Santos and Christy Heaton. The authors are thankful to Flavio da Silva Coelho for help with radiocarbon dating calibrations, Victor A. Albert for valuable comments on the manuscript, and Dilek Koptekin for insightful discussions during the review process. This research was supported with funding from the National Science Foundation (grant nos. 1556565 , 1854550 , 9870343 , and 0208247 ) and the National Geographic Society (grant no. 6212-98 ).",
year = "2023",
month = may,
day = "19",
doi = "10.1016/j.isci.2023.106581",
language = "English (US)",
volume = "26",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
number = "5",
}