A novel head-neck cooling device for concussion injury in contact sports

Huan Wang, Bonnie Wang, Kevin Jackson, Claire M. Miller, Linda Hasadsri, Daniel Llano, Rachael Rubin, Jarred Zimmerman, Curtis Johnson, Brad Sutton

Research output: Contribution to journalArticle

Abstract

Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports.

Original languageEnglish (US)
Pages (from-to)20-31
Number of pages12
JournalTranslational Neuroscience
Volume6
DOIs
StatePublished - Jan 1 2015

Fingerprint

Brain Concussion
Sports
Neck
Hypothermia
Head
United States National Aeronautics and Space Administration
Equipment and Supplies
Wounds and Injuries
Brain
Space Suits
Technology
Temperature
Therapeutics
Disease Management
Craniocerebral Trauma
Athletes
Research

Keywords

  • Brain hypothermia
  • Brain temperature
  • Head-neck cooling
  • Mild traumatic brain injury
  • Sports

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

A novel head-neck cooling device for concussion injury in contact sports. / Wang, Huan; Wang, Bonnie; Jackson, Kevin; Miller, Claire M.; Hasadsri, Linda; Llano, Daniel; Rubin, Rachael; Zimmerman, Jarred; Johnson, Curtis; Sutton, Brad.

In: Translational Neuroscience, Vol. 6, 01.01.2015, p. 20-31.

Research output: Contribution to journalArticle

Wang, H, Wang, B, Jackson, K, Miller, CM, Hasadsri, L, Llano, D, Rubin, R, Zimmerman, J, Johnson, C & Sutton, B 2015, 'A novel head-neck cooling device for concussion injury in contact sports', Translational Neuroscience, vol. 6, pp. 20-31. https://doi.org/10.1515/tnsci-2015-0004
Wang, Huan ; Wang, Bonnie ; Jackson, Kevin ; Miller, Claire M. ; Hasadsri, Linda ; Llano, Daniel ; Rubin, Rachael ; Zimmerman, Jarred ; Johnson, Curtis ; Sutton, Brad. / A novel head-neck cooling device for concussion injury in contact sports. In: Translational Neuroscience. 2015 ; Vol. 6. pp. 20-31.
@article{b0021eb58d214eb0a8441b54512911df,
title = "A novel head-neck cooling device for concussion injury in contact sports",
abstract = "Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports.",
keywords = "Brain hypothermia, Brain temperature, Head-neck cooling, Mild traumatic brain injury, Sports",
author = "Huan Wang and Bonnie Wang and Kevin Jackson and Miller, {Claire M.} and Linda Hasadsri and Daniel Llano and Rachael Rubin and Jarred Zimmerman and Curtis Johnson and Brad Sutton",
year = "2015",
month = "1",
day = "1",
doi = "10.1515/tnsci-2015-0004",
language = "English (US)",
volume = "6",
pages = "20--31",
journal = "Translational Neuroscience",
issn = "2081-3856",
publisher = "de Gruyter",

}

TY - JOUR

T1 - A novel head-neck cooling device for concussion injury in contact sports

AU - Wang, Huan

AU - Wang, Bonnie

AU - Jackson, Kevin

AU - Miller, Claire M.

AU - Hasadsri, Linda

AU - Llano, Daniel

AU - Rubin, Rachael

AU - Zimmerman, Jarred

AU - Johnson, Curtis

AU - Sutton, Brad

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports.

AB - Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports.

KW - Brain hypothermia

KW - Brain temperature

KW - Head-neck cooling

KW - Mild traumatic brain injury

KW - Sports

UR - http://www.scopus.com/inward/record.url?scp=84928478645&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928478645&partnerID=8YFLogxK

U2 - 10.1515/tnsci-2015-0004

DO - 10.1515/tnsci-2015-0004

M3 - Article

VL - 6

SP - 20

EP - 31

JO - Translational Neuroscience

JF - Translational Neuroscience

SN - 2081-3856

ER -