A novel CDK2/9 inhibitor CYC065 causes anaphase catastrophe and represses proliferation, tumorigenesis, and metastasis in aneuploid cancers

Masanori Kawakami, Lisa Maria Mustachio, Yulong Chen, Zibo Chen, Xiuxia Liu, Cheng Hsin Wei, Jason Roszik, Adam S. Kittai, Alexey V. Danilov, Xiaoshan Zhang, Bingliang Fang, Jing Wang, John V. Heymach, Liliya Tyutyunyk-Massey, Sarah J. Freemantle, Jonathan M. Kurie, Xi Liu, Ethan Dmitrovsky

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Medicine & Life Sciences