@article{a146bd8c844044a3b86aa7e58f93c77a,
title = "A Newly Synthesized Tris(crown ether) Ionophore for Assisted Ion Transfer at NanoITIES Electrodes",
abstract = "Assisted ion transfer at a pipet-supported interface between two immiscible electrolyte solutions (ITIES) have become a prominent method for the detection of various ionic species and for studying ionic complexation. A typical ionophore contains one binding center to ions such as dibenzo-18-crown-6 (DB18C6). It is unknown how the detection of ions changes when assisted by an ionophore with multiple crown ether moieties. Here, we synthesized a new tris(crown ether) ionophore, TriBCE, which is composed of three 18-crown-6 moieties connected to a common o-phenylene ethynylene cyclic trimer center, and employed TriBCE for the assisted ion transfer of various environmentally relevant heavy-metal ions (i. e. Mg2+, Cu2+, Cd2+ and Li+) and a neurotransmitter (dopamine) at nanoITIES pipet electrodes. The half-wave transfer potentials for those ions were less positive by 123±28 mV when assisted by tris (crown ether), TriBCE, compared to mono(crown ether), DB18C6. The binding constants, Gibbs free energy, and the stoichiometric coefficients of ionic complexation with TriBCE were measured and compared to that of DB18C6 to reveal that ionophore with multiple binding moieties enables easier transfer of these ions.",
keywords = "DB18C6, cyclic voltammetry, ion transfer, nanoITIES, tris(crown ether)",
author = "Ran Chen and Anna Yang and Albert Chang and Oweimrin, {Philip F.} and Julian Romero and Pitchaya Vichitcharoenpaisarn and Stephanie Tapia and Kevin Ha and Christopher Villaflor and Mei Shen",
note = "Funding Information: The authors thank the National Science Foundation for financial support with a CAREER award (CHE 19‐45274) to M.S. as well as the support from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (R21NS085665), and University of Illinois at Urbana‐Champaign. A.Y. is a co‐author in this manuscript and would like to acknowledge the support from the National Science Foundation under grant number CHE 16–10328. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or National Science Foundation. The authors are grateful for the helpful and thoughtful discussions from Prof. Jeffrey Moore. A.C. is grateful for the support from John E. Gieseking Scholarship for summer research. , , , Funding Information: The authors thank the National Science Foundation for financial support with a CAREER award (CHE 19-45274) to M.S. as well as the support from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (R21NS085665), and University of Illinois at Urbana-Champaign. A.Y. is a co-author in this manuscript and would like to acknowledge the support from the National Science Foundation under grant number CHE 16?10328. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or National Science Foundation. The authors are grateful for the helpful and thoughtful discussions from Prof. Jeffrey Moore. A.C. is grateful for the support from John E. Gieseking Scholarship for summer research. Publisher Copyright: {\textcopyright} 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2020",
month = feb,
day = "17",
doi = "10.1002/celc.201901997",
language = "English (US)",
volume = "7",
pages = "967--974",
journal = "ChemElectroChem",
issn = "2196-0216",
publisher = "John Wiley & Sons, Ltd.",
number = "4",
}