A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TR LRET assays

Sung Hoon Kim, Pinghua Ge, John A. Katzenellenbogen

Research output: Contribution to journalArticlepeer-review

Abstract

A quinoline sensitizer-centered lanthanide chelate system of novel design for TR-LRET was prepared; it exhibited high labelling efficiency with a his-tagged protein (ERα-LBD) on the Ni-NTA beads, using a mixed metal chelate protocol, and it functioned well in TR-LRET protein-protein interaction assays.

Original languageEnglish (US)
Pages (from-to)183-185
Number of pages3
JournalChemical Communications
Issue number2
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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