A new frontier in soy bioactive peptides that may prevent age-related chronic diseases

Research output: Contribution to journalReview articlepeer-review


During gastrointestinal digestion or food processing of proteins, small peptides can be released and may act as regulatory compounds with hormone-like activities. Numerous biologically active peptides (bioactive peptides) have been identified. Most bioactive peptides are derived from milk and dairy products, with the most common being angiotensin converting enzyme inhibitory peptides. Soybean protein and soybean derived peptides also play an important role in soybean physiological activities, particularly those related to the prevention of chronic diseases. However, the bioactive potential of soybean derived bioactive peptides is yet to be fully appreciated. After a general introduction of approaches and advances in bioactive peptides from food sources, this review focuses on bioactive peptides derived from soybean proteins and their physiological properties. Technological approaches to generate bioactive peptides, their isolation, purification, characterization, and quantification, and further application in food and drug design are also presented. Safety concerns, such as potential toxicity, allergenicity, and sensory aspect of these peptides are likewise discussed.

Original languageEnglish (US)
Pages (from-to)63-78
Number of pages16
JournalComprehensive Reviews in Food Science and Food Safety
Issue number4
StatePublished - 2005


  • Antihypertensive
  • Antiobesity
  • Bioactive peptides
  • Hypocholesterolemic
  • Soybean

ASJC Scopus subject areas

  • Food Science


Dive into the research topics of 'A new frontier in soy bioactive peptides that may prevent age-related chronic diseases'. Together they form a unique fingerprint.

Cite this