@article{aa6067c9afea4fd49d2d6e66fed46dae,
title = "A new approach towards the synthesis of bielschowskysin: Synthesis and photochemistry of an advanced macrocyclic enedione intermediate",
abstract = "A novel approach towards bielschowskysin is reported based on an attempted stepwise cyclobutane formation. Synthesis of the key strained framework, containing the tricyclic ring system and all requisite carbons has been developed. While photochemical studies did not result in a late-stage Norrish–Yang cyclization, the observed isomerization could provide important insights into the synthesis of other furanocembranoids.",
keywords = "Bielschowskysin, Enedione, Furanocembranoids, Norrish–Yang, Nozaki–Hiyama–Kishi",
author = "Marko Nesic and Kincanon, {Maegen M.} and Ryffel, {David B.} and David Sarlah",
note = "Funding Information: Financial support for this work was provided by the University of Illinois. Amgen, Eli Lilly, and Bristol-Myers Squibb are also acknowledged for unrestricted research support. We also thank Dr. D. Olson and Dr. L. Zhu for NMR spectroscopic assistance, Dr. D. L. Gray, Dr. T. Woods and Mr. A. Shved for X-ray crystallographic analysis assistance, and F. Sun for mass spectrometric assistance. Funding Information: Financial support for this work was provided by the University of Illinois . Amgen, Eli Lilly, and Bristol-Myers Squibb are also acknowledged for unrestricted research support. We also thank Dr. D. Olson and Dr. L. Zhu for NMR spectroscopic assistance, Dr. D. L. Gray, Dr. T. Woods and Mr. A. Shved for X-ray crystallographic analysis assistance, and F. Sun for mass spectrometric assistance. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2020",
month = dec,
day = "18",
doi = "10.1016/j.tet.2020.131318",
language = "English (US)",
volume = "76",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "51",
}