A mutant of Escherichia coli auxotrophic for organic phosphates: Evidence for two defects in inorganic phosphate transport

George F. Sprague, Robert M. Bell, John E Cronan

Research output: Contribution to journalArticle

Abstract

An inorganic phosphate transport mutant has been isolated as a sn-glycerol-3-phosphate auxotroph and characterized genetically. Two lesions are responsible for the transport defect. One lesion, pst, is located at minute 74 of the E. coli genetic map while the other lesion, pit, is located at minute 68. All "K10" strains that were examined carry the pit lesion. Evidence is presented that the glycerol phosphate and hexose phosphate transport systems. The mapping data indicate that the genetic distance between malA and xyl is greater than that now allowed.

Original languageEnglish (US)
Pages (from-to)71-77
Number of pages7
JournalMGG Molecular & General Genetics
Volume143
Issue number1
DOIs
StatePublished - Jan 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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