A Highly Selective Catalytic Method for the Oxidative Functionalization of C-H Bonds

Allison R. Dick, Kami L. Hull, Melanie S. Sanford

Research output: Contribution to journalArticle

Abstract

This communication describes a new and highly practical Pd(II)-catalyzed method for the regio- and chemoselective oxidative functionalization of arenes and alkanes. Carbon?hydrogen bonds of substrates that contain a variety of directing groups (e.g., pyridine, azobenzene, pyrazole, and imine derivatives) are selectively transformed into esters, ethers, and aryl-halides under mild conditions. The scope of this reaction in terms of substrate, directing group, and oxidant is described, and a preliminary catalytic cycle is proposed.

Original languageEnglish (US)
Pages (from-to)2300-2301
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number8
DOIs
StatePublished - Mar 3 2004

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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