A Forced March across an RNA Folding Landscape

Research output: Contribution to journalShort surveypeer-review


In a recent issue of Science, Greenleaf et al. (2008) report single-molecule force measurements to explore the sequential folding landscape of an adenine riboswitch aptamer domain. This study provides an exceptionally quantitative view of how an RNA molecule folds.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
JournalChemistry and Biology
Issue number3
StatePublished - Mar 21 2008

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


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