A field guide to foldamers

David J. Hill; Matthew J. Mio; Ryan B. Prince; Thomas S. Hughes; Jeffrey S. Moore

doi:10.1021/cr990120t

A field guide to foldamers

David J. Hill, Matthew J. Mio, Ryan B. Prince, Thomas S. Hughes, Jeffrey S. Moore

Research output: Contribution to journal › Review article › peer-review

Abstract

The conformational control in synthetic chain molecules of foldamers were studied. The accumulation of noncovalent interactions that dictated conformation had no direct counterpart in small molecule chemistry. The results showed that the van der Waals and solvophobic interactions were crucial in foldamer designs.

Original language	English (US)
Pages (from-to)	3893-4011
Number of pages	119
Journal	Chemical reviews
Volume	101
Issue number	12
DOIs	https://doi.org/10.1021/cr990120t
State	Published - Dec 1 2001

ASJC Scopus subject areas

Chemistry(all)

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10.1021/cr990120t

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title = "A field guide to foldamers",

abstract = "The conformational control in synthetic chain molecules of foldamers were studied. The accumulation of noncovalent interactions that dictated conformation had no direct counterpart in small molecule chemistry. The results showed that the van der Waals and solvophobic interactions were crucial in foldamer designs.",

author = "Hill, {David J.} and Mio, {Matthew J.} and Prince, {Ryan B.} and Hughes, {Thomas S.} and Moore, {Jeffrey S.}",

year = "2001",

month = dec,

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doi = "10.1021/cr990120t",

language = "English (US)",

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AU - Mio, Matthew J.

AU - Prince, Ryan B.

AU - Hughes, Thomas S.

AU - Moore, Jeffrey S.

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N2 - The conformational control in synthetic chain molecules of foldamers were studied. The accumulation of noncovalent interactions that dictated conformation had no direct counterpart in small molecule chemistry. The results showed that the van der Waals and solvophobic interactions were crucial in foldamer designs.

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