A fabrication of a novel microfluidic reactor microsynthesis of MIP's particles

Kyung M. Choi, John A Rogers, Kenneth J. Shea

Research output: Contribution to journalConference article

Abstract

Microfabrication offers us the ability to fabricate numerous active devices at the micro-scale by patterning features on a variety of substrates for developing small devices in nanotechnology. Since materials scientists and chemists have been looking for unconventional approaches in the synthesis of novel materials, we introduce here a novel strategy of fabricating microfluidic reactors. A new microfluidic reactor was designed and fabricated for the microscale synthesis of materials, which has not been possible from conventional bulk syntheses. The microreactor presents a continuous, dynamic droplet generation. Using the microfluidic reactor, we demonstrate here a microfluidic synthesis of molecularly imprinted polymer (MIP), which is useful for bio- or chemical sensor applications due to its specific molecular recognition functions. Since the particle size of MIP's system directly affects their affinity capability in molecular recognitions, uniform MIPs' particles at the nano- or micro-scale were produced via the microfluidic technique to achieve high sensitivity by developing 'monoclonal' MIPs particles, which have only high affinity binding sites.

Original languageEnglish (US)
Article numberJ9.4
Pages (from-to)137-141
Number of pages5
JournalMaterials Research Society Symposium Proceedings
Volume872
StatePublished - Dec 1 2005
Event2005 Materials Research Society Spring Meeting - San Francisco, CA, United States
Duration: Mar 28 2005Apr 1 2005

Fingerprint

Microfluidics
reactors
Fabrication
fabrication
synthesis
Molecular recognition
affinity
nanotechnology
microbalances
Microfabrication
Binding sites
Chemical sensors
Nanotechnology
Polymers
Particle size
Binding Sites
sensitivity
sensors
polymers
Substrates

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

A fabrication of a novel microfluidic reactor microsynthesis of MIP's particles. / Choi, Kyung M.; Rogers, John A; Shea, Kenneth J.

In: Materials Research Society Symposium Proceedings, Vol. 872, J9.4, 01.12.2005, p. 137-141.

Research output: Contribution to journalConference article

Choi, Kyung M. ; Rogers, John A ; Shea, Kenneth J. / A fabrication of a novel microfluidic reactor microsynthesis of MIP's particles. In: Materials Research Society Symposium Proceedings. 2005 ; Vol. 872. pp. 137-141.
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