TY - JOUR
T1 - A distinct symptom pattern emerges for COVID-19 long-haul
T2 - a nationwide study
AU - Pinto, Melissa D.
AU - Downs, Charles A.
AU - Huang, Yong
AU - El-Azab, Sarah A.
AU - Ramrakhiani, Nathan S.
AU - Barisano, Anthony
AU - Yu, Lu
AU - Taylor, Kaitlyn
AU - Esperanca, Alvaro
AU - Abrahim, Heather L.
AU - Hughes, Thomas
AU - Herrera, Maria Giraldo
AU - Rahamani, Amir M.
AU - Dutt, Nikil
AU - Chakraborty, Rana
AU - Mendiola, Christian
AU - Lambert, Natalie
N1 - We would like to thank Survivor Corps for mobilizing their members to participate in this study and for accelerating long covid research while connecting, supporting, and educating those affected by COVID-19. We would also like to thank the Precision Health Initiative at Indiana University for their support on this project.
PY - 2022/12
Y1 - 2022/12
N2 - Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom type and onset) among a nationwide sample of PASC survivors (n = 5652). The sample was randomly sorted into two independent samples for exploratory (EFA) and confirmatory factor analyses (CFA). Five factors emerged from the EFA: (1) cold and flu-like symptoms, (2) change in smell and/or taste, (3) dyspnea and chest pain, (4) cognitive and visual problems, and (5) cardiac symptoms. The CFA had excellent model fit (x2 = 513.721, df = 207, p < 0.01, TLI = 0.952, CFI = 0.964, RMSEA = 0.024). These findings demonstrate a novel symptom pattern for PASC. These findings can enable nurses in the identification of at-risk patients and facilitate early, systematic symptom management strategies for PASC.
AB - Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom type and onset) among a nationwide sample of PASC survivors (n = 5652). The sample was randomly sorted into two independent samples for exploratory (EFA) and confirmatory factor analyses (CFA). Five factors emerged from the EFA: (1) cold and flu-like symptoms, (2) change in smell and/or taste, (3) dyspnea and chest pain, (4) cognitive and visual problems, and (5) cardiac symptoms. The CFA had excellent model fit (x2 = 513.721, df = 207, p < 0.01, TLI = 0.952, CFI = 0.964, RMSEA = 0.024). These findings demonstrate a novel symptom pattern for PASC. These findings can enable nurses in the identification of at-risk patients and facilitate early, systematic symptom management strategies for PASC.
UR - https://www.scopus.com/pages/publications/85138458121
UR - https://www.scopus.com/pages/publications/85138458121#tab=citedBy
U2 - 10.1038/s41598-022-20214-7
DO - 10.1038/s41598-022-20214-7
M3 - Article
C2 - 36151129
AN - SCOPUS:85138458121
SN - 2045-2322
VL - 12
JO - Scientific reports
JF - Scientific reports
IS - 1
M1 - 15905
ER -