A convenient synthesis of chiral N-Boc-amino ethers as potential peptide bond surrogate units

Mengfei Ho; James K.K. Chung; Nancy Tang

doi:10.1016/0040-4039(93)88092-W

A convenient synthesis of chiral N-Boc-amino ethers as potential peptide bond surrogate units

Mengfei Ho, James K.K. Chung, Nancy Tang

Research output: Contribution to journal › Article › peer-review

Abstract

Boron triflouride etherate and zinc triflate have been found to be effective catalysists for the synthetic route to chiral N-Boc-amino ethers via a Lewis acid-catalyzed ring-opening of N-acyl aziridines, derived from chiral amino acids.

Original language	English (US)
Pages (from-to)	6513-6516
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	41
DOIs	https://doi.org/10.1016/0040-4039(93)88092-W
State	Published - Oct 8 1993
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "A convenient synthesis of chiral N-Boc-amino ethers as potential peptide bond surrogate units",

abstract = "Boron triflouride etherate and zinc triflate have been found to be effective catalysists for the synthetic route to chiral N-Boc-amino ethers via a Lewis acid-catalyzed ring-opening of N-acyl aziridines, derived from chiral amino acids.",

author = "Mengfei Ho and Chung, {James K.K.} and Nancy Tang",

year = "1993",

month = oct,

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doi = "10.1016/0040-4039(93)88092-W",

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publisher = "Elsevier Limited",

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AU - Ho, Mengfei

AU - Chung, James K.K.

AU - Tang, Nancy

PY - 1993/10/8

Y1 - 1993/10/8

N2 - Boron triflouride etherate and zinc triflate have been found to be effective catalysists for the synthetic route to chiral N-Boc-amino ethers via a Lewis acid-catalyzed ring-opening of N-acyl aziridines, derived from chiral amino acids.

AB - Boron triflouride etherate and zinc triflate have been found to be effective catalysists for the synthetic route to chiral N-Boc-amino ethers via a Lewis acid-catalyzed ring-opening of N-acyl aziridines, derived from chiral amino acids.

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U2 - 10.1016/0040-4039(93)88092-W

DO - 10.1016/0040-4039(93)88092-W

M3 - Article

AN - SCOPUS:0027517214

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

A convenient synthesis of chiral N-Boc-amino ethers as potential peptide bond surrogate units

Abstract

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