A conserved histone variant enriched in nucleoli of mammalian cells

C. David Allis, Yvonne Sanford Ziegler, Martin A. Gorovsky, J. B. Olmsted

Research output: Contribution to journalArticlepeer-review

Abstract

An antibody has been raised to Tetrahymena histone variant hv1 that specifically stains the macronucleus, but not the micronucleus, of Tetrahymena. This antiserum also stains small punctate regions in nucleoli of several mammalian cell lines. These observations suggest that this histone variant has been highly conserved in evolution and may be associated with transcribed sequences.

Original languageEnglish (US)
Pages (from-to)131-136
Number of pages6
JournalCell
Volume31
Issue number1
DOIs
StatePublished - Nov 1982
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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