A conditional probabilistic model for joint analysis of symptoms, diseases, and herbs in traditional Chinese medicine patient records

Sheng Wang, Edward W. Huang, Runshun Zhang, Xiaoping Zhang, Baoyan Liu, Xuezhong Zhou, Chengxiang Zhai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Traditional Chinese medicine (TCM) can provide important complementary medical care to modern medicine, and is widely practiced in China and many other countries. Unfortunately, due to its empirical nature and history of trial and error, effective diagnosis and prescription methods are not well-defined. This setback results in a significant challenge in retaining, sharing, and inheriting knowledge among physicians. In this paper, we propose a new asymmetric probabilistic model for the joint analysis of symptoms, diseases, and herbs in patient records to discover and extract latent TCM knowledge. We base our model on the comprehensive evaluation of modern medicine and TCM-specific symptoms in addition to herb prescriptions for particular diseases. Experimental results on a large dataset demonstrate the effectiveness of the proposed model for discovering useful knowledge and its potential clinical applications.

Original languageEnglish (US)
Title of host publicationProceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016
EditorsKevin Burrage, Qian Zhu, Yunlong Liu, Tianhai Tian, Yadong Wang, Xiaohua Tony Hu, Qinghua Jiang, Jiangning Song, Shinichi Morishita, Kevin Burrage, Guohua Wang
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages411-418
Number of pages8
ISBN (Electronic)9781509016105
DOIs
StatePublished - Jan 17 2017
Event2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016 - Shenzhen, China
Duration: Dec 15 2016Dec 18 2016

Publication series

NameProceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016

Other

Other2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016
Country/TerritoryChina
CityShenzhen
Period12/15/1612/18/16

ASJC Scopus subject areas

  • Genetics
  • Medicine (miscellaneous)
  • Genetics(clinical)
  • Biochemistry, medical
  • Biochemistry
  • Molecular Medicine
  • Health Informatics

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