Abstract
(Chemical Equation Presented) Skip the chiral ligand: A chiral Lewis acid strategy for effecting asymmetric induction in oxidative systems not amenable to strongly binding chiral ligands is disclosed and its mechanism investigated. The highest levels of enantioselectivity for allylic C-H oxidation of terminal olefins is reported (see scheme; BQ=1,4-benzoquinone, LA*=chiral Lewis acid).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6448-6451 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 47 |
| Issue number | 34 |
| DOIs | |
| State | Published - Aug 11 2008 |
Keywords
- Allylic oxidation
- C-H activation
- Enantioselectivity
ASJC Scopus subject areas
- Catalysis
- General Chemistry