A catalytic role for methionine revealed by a combination of computation and experiments on phosphite dehydrogenase

Keyphrases

• Methionine 100%
• Phosphite Dehydrogenase 100%
• Catalytic Role 100%
• Quantum Mechanics-molecular Mechanics 66%
• Metal Ions 33%
• Side Chain 33%
• Protein Structure 33%
• Norleucine 33%
• Phosphite 33%
• Interaction Type 33%
• Transition State 33%
• Binding Effect 33%
• Kcat 33%
• Binding Interaction 33%
• Reaction Mechanism 33%
• Steric Effect 33%
• Hydride Transfer 33%
• Cambridge Structural Database 33%
• Protein Data Bank 33%
• Molecular Mechanics Simulation 33%
• Enzyme-catalyzed Reaction 33%
• Catalytic Effect 33%
• Structure of Mechanism 33%
• QM Calculation 33%

Chemistry

• Methionine 100%
• Quantum Mechanics 100%
• Catalysis 100%
• Molecular Mechanic 100%
• Structure 50%
• Selenomethionine 50%
• Metal Ion 50%
• Transition State 50%
• Protein Structure 50%
• Kcat 50%
• Enzymatic Reaction 50%

Biochemistry, Genetics and Molecular Biology

• Oxidoreductase 100%
• Dehydrogenase 100%
• Methionine 100%
• Molecular Mechanic 66%
• Quantum Mechanics 66%
• Static Electricity 33%
• Enzyme 33%
• Selenomethionine 33%
• Protein Structure 33%
• Turnover Number 33%
• Enzyme Mechanism 33%
• Protein Data Bank 33%
• Structural Database 33%