A bubble-driven microfluidic transport element for bioengineering

Philippe Marmottant, Sascha Hilgenfeldt

Research output: Contribution to journalArticle

Abstract

Microfluidics typically uses channels to transport small objects by actuation forces such as an applied pressure difference or thermocapillarity. We propose that acoustic streaming is an alternative means of directional transport at small scales. Microbubbles on a substrate establish well controlled fluid motion on very small scales; combinations ("doublets") of bubbles and microparticles break the symmetry of the motion and constitute flow transport elements. We demonstrate the principle of doublet streaming and describe the ensuing transport. Devices based on doublet flow elements work without microchannels and are thus potentially cheap and highly parallelizable.

Original languageEnglish (US)
Pages (from-to)9523-9527
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume101
Issue number26
DOIs
StatePublished - Jun 29 2004
Externally publishedYes

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Bioengineering
Microfluidics
Microbubbles
Acoustics
Pressure
Equipment and Supplies

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

A bubble-driven microfluidic transport element for bioengineering. / Marmottant, Philippe; Hilgenfeldt, Sascha.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 26, 29.06.2004, p. 9523-9527.

Research output: Contribution to journalArticle

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