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  3D Printed Stem-Cell-Laden, Microchanneled Hydrogel Patch for the Enhanced Release of Cell-Secreting Factors and Treatment of Myocardial Infarctions

  Melhem, M. R., Park, J., Knapp, L., Reinkensmeyer, L., Cvetkovic, C., Flewellyn, J., Lee, M. K., Jensen, T. W., Bashir, R., Kong, H. & Schook, L. B., Sep 11 2017, In: ACS Biomaterials Science and Engineering. 3, 9, p. 1980-1987 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem cells
  • Hydrogels
  • Polyethylene Glycol Dimethacrylate Hydrogel
  • Gels
  • Microchannels

• 3D printing enables separation of orthogonal functions within a hydrogel particle

  Raman, R., Clay, N. E., Sen, S., Melhem, M., Qin, E., Kong, H. & Bashir, R., Jan 1 2016, In: Biomedical microdevices. 18, 3, 49.

  Research output: Contribution to journal › Article › peer-review

  • Orthogonal functions
  • Three-Dimensional Printing
  • Hydrogels
  • Iron oxides
  • Polyethylene glycols

• A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes

  Watkins, N. N., Sridhar, S., Cheng, X., Chen, G. D., Toner, M., Rodriguez, W. & Bashir, R., Apr 21 2011, In: Lab on a chip. 11, 8, p. 1437-1447 11 p.

  Research output: Contribution to journal › Article › peer-review

  • T-cells
  • T-Lymphocytes
  • Leukocytes
  • Immobilized Antibodies
  • Cell Count

• A microfluidic biochip platform for electrical quantification of proteins

  Valera, E., Berger, J., Hassan, U., Ghonge, T., Liu, J., Rappleye, M., Winter, J., Abboud, D., Haidry, Z., Healey, R., Hung, N. T., Leung, N., Mansury, N., Hasnain, A., Lannon, C., Price, Z., White, K. & Bashir, R., May 21 2018, In: Lab on a chip. 18, 10, p. 1461-1470 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Biochips
  • Biomarkers
  • Microfluidics
  • Proteins
  • Sepsis

• A microfluidic technique to estimate antigen expression on particles

  Ghonge, T., Ganguli, A., Valera, E., Saadah, M., Damhorst, G. L., Berger, J., Pagan Diaz, G., Hassan, U., Chheda, M., Haidry, Z., Liu, S., Hwu, C. & Bashir, R., Dec 1 2017, In: APL Bioengineering. 1, 1, 016103.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antigens
  • Microfluidics
  • neutravidin
  • Assays
  • Biotin

• A modular approach to the design, fabrication, and characterization of muscle-powered biological machines

  Raman, R., Cvetkovic, C. & Bashir, R., Mar 1 2017, In: Nature Protocols. 12, 3, p. 519-533 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Skeleton
  • Muscle
  • Actuators
  • Fabrication
  • Muscles

• A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification

  Hassan, U., Ghonge, T., Reddy, B., Patel, M., Rappleye, M., Taneja, I., Tanna, A., Healey, R., Manusry, N., Price, Z., Jensen, T., Berger, J., Hasnain, A., Flaugher, E., Liu, S., Davis, B., Kumar, J., White, K. & Bashir, R., Jul 3 2017, In: Nature communications. 8, 15949.

  Research output: Contribution to journal › Article › peer-review

  • Biochips
  • leukocytes
  • Microfluidics
  • stratification
  • Point-of-Care Systems

• Biaxial Dielectrophoresis Force Spectroscopy: A Stoichiometric Approach for Examining Intermolecular Weak Binding Interactions

  Park, I. S., Kwak, T. J., Lee, G., Son, M., Choi, J. W., Choi, S., Nam, K., Lee, S. Y., Chang, W. J., Eom, K., Yoon, D. S., Lee, S., Bashir, R. & Lee, S. W., Apr 26 2016, In: ACS Nano. 10, 4, p. 4011-4019 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrophoresis
  • Spectroscopy
  • loading rate
  • pulling
  • spectroscopy

• Biodegradable Monocrystalline Silicon Photovoltaic Microcells as Power Supplies for Transient Biomedical Implants

  Lu, L., Yang, Z., Meacham, K., Cvetkovic, C., Corbin, E. A., Vázquez-Guardado, A., Xue, M., Yin, L., Boroumand, J., Pakeltis, G., Sang, T., Yu, K. J., Chanda, D., Bashir, R., Gereau, R. W., Sheng, X. & Rogers, J. A., Jun 5 2018, In: Advanced Energy Materials. 8, 16, 1703035.

  Research output: Contribution to journal › Article › peer-review

  • Monocrystalline silicon
  • Oils and fats
  • Wavelength
  • Skin
  • Tissue

• Biomimicry, Biofabrication, and Biohybrid Systems: The Emergence and Evolution of Biological Design

  Raman, R. & Bashir, R., Oct 25 2017, In: Advanced Healthcare Materials. 6, 20, 1700496.

  Research output: Contribution to journal › Article › peer-review

  • Biological Evolution
  • Curriculum
  • History
  • Curricula
  • Systems analysis

• Characterization of a 1024 × 1024 DG-BioFET platform

  Duarte-Guevara, C., Swaminathan, V., Reddy, B., Wen, C. H., Huang, Y. J., Huang, J. C., Liu, Y. S. & Bashir, R., 2017, In: Sensors and Actuators, B: Chemical. 250, p. 100-110 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Field effect transistors
  • platforms
  • Amplification
  • field effect transistors
  • characterization

• Combining Biomarkers with EMR Data to Identify Patients in Different Phases of Sepsis

  Taneja, I., Reddy, B., Damhorst, G., Dave Zhao, S., Hassan, U., Price, Z., Jensen, T., Ghonge, T., Patel, M., Wachspress, S., Winter, J., Rappleye, M., Smith, G., Healey, R., Ajmal, M., Khan, M., Patel, J., Rawal, H., Sarwar, R., Soni, S. & 6 others, Anwaruddin, S., Davis, B., Kumar, J., White, K., Bashir, R. & Zhu, R., Dec 1 2017, In: Scientific reports. 7, 1, 10800.

  Research output: Contribution to journal › Article › peer-review

  • Electronic Health Records
  • Sepsis
  • Biomarkers
  • Area Under Curve
  • Interleukin 1 Receptor Antagonist Protein

• Control of nanoscale environment to improve stability of immobilized proteins on diamond surfaces

  Radadia, A. D., Stavis, C. J., Carr, R., Zeng, H., King, W. P., Carlisle, J. A., Aksimentiev, A., Hamers, R. J. & Bashir, R., Mar 22 2011, In: Advanced Functional Materials. 21, 6, p. 1040-1050 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Immobilized Proteins
  • Diamond
  • Diamonds
  • Proteins
  • proteins

• Damage, Healing, and Remodeling in Optogenetic Skeletal Muscle Bioactuators

  Raman, R., Grant, L., Seo, Y., Cvetkovic, C., Gapinske, M., Palasz, A., Dabbous, H., Kong, H., Pinera, P. P. & Bashir, R., Jun 21 2017, In: Advanced Healthcare Materials. 6, 12, 1700030.

  Research output: Contribution to journal › Article › peer-review

  • Optogenetics
  • Muscle
  • Skeletal Muscle
  • Three-Dimensional Printing
  • Technology

• Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum

  Raman, R., Mitchell, M., Perez-Pinera, P., Bashir, R. & DeStefano, L., Sep 21 2016, In: Journal of Biological Engineering. 10, 1, 10.

  Research output: Contribution to journal › Article › peer-review

  • Biomedical Engineering
  • Biomedical engineering
  • Curricula
  • Curriculum
  • Students

• Detecting sepsis by observing neutrophil motility

  Hassan, U., Valera, E. & Bashir, R., Apr 1 2018, In: Nature biomedical engineering. 2, 4, p. 197-198 2 p.

  Research output: Contribution to journal › Article › peer-review

• Detection of methylation on dsDNA using nanopores in a MoS₂ membrane

  Shim, J., Banerjee, S., Qiu, H., Smithe, K. K. H., Estrada, D., Bello, J., Pop, E., Schulten, K. & Bashir, R., Oct 31 2017, In: Nanoscale. 9, 39, p. 14836-14845 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • Nanopores
  • Membranes
  • DNA
  • Carrier Proteins

• Detection of silver ions using dielectrophoretic tweezers-based force spectroscopy

  Choi, S., Lee, G., Park, I. S., Son, M., Kim, W., Lee, H., Lee, S. Y., Na, S., Yoon, D. S., Bashir, R., Park, J. & Lee, S. W., Jan 1 2016, In: Analytical chemistry. 88, 22, p. 10867-10875 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Polynucleotides
  • Spectroscopy
  • Silver
  • Metal ions
  • Heavy ions

• Direct characterization of hydrodynamic loading on a microelectromechanical systems microstructure

  Mehrnezhad, A., Bashir, R. & Park, K., Mar 14 2016, In: Applied Physics Letters. 108, 11, 114101.

  Research output: Contribution to journal › Article › peer-review

  • microelectromechanical systems
  • hydrodynamics
  • microstructure
  • characterization
  • viscous fluids

• Dynamic mechanical measurement of the viscoelasticity of single adherent cells

  Corbin, E. A., Adeniba, O. O., Ewoldt, R. H. & Bashir, R., Feb 29 2016, In: Applied Physics Letters. 108, 9, 093701.

  Research output: Contribution to journal › Article › peer-review

  • mechanical measurement
  • viscoelasticity
  • cells
  • sensors
  • microelectromechanical systems

• Electrical detection of dsDNA and polymerase chain reaction amplification

  Salm, E., Liu, Y. S., Marchwiany, D., Morisette, D., He, Y., Bhunia, A. K. & Bashir, R., Dec 2011, In: Biomedical microdevices. 13, 6, p. 973-982 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Polymerase chain reaction
  • DNA
  • Amplification
  • Pathogens
  • Deionized water

• Evidence of differential mass change rates between human breast cancer cell lines in culture

  Corbin, E. A., Adeniba, O. O., Cangellaris, O. V., King, W. P. & Bashir, R., Mar 1 2017, In: Biomedical microdevices. 19, 1, 10.

  Research output: Contribution to journal › Article › peer-review

  • Cell culture
  • Cells
  • Breast Neoplasms
  • Cell Line
  • Growth

• Hands-free smartphone-based diagnostics for simultaneous detection of Zika, Chikungunya, and Dengue at point-of-care

  Ganguli, A., Ornob, A., Yu, H., Damhorst, G. L., Chen, W., Sun, F., Bhuiya, A., Cunningham, B. T. & Bashir, R., Dec 1 2017, In: Biomedical microdevices. 19, 4, 73.

  Research output: Contribution to journal › Article › peer-review

  • Smartphone
  • Dengue
  • Point-of-Care Systems
  • Smartphones
  • Blood

• High-k dielectric Al₂O₃ nanowire and nanoplate field effect sensors for improved pH sensing

  Reddy, B., Dorvel, B. R., Go, J., Nair, P. R., Elibol, O. H., Credo, G. M., Daniels, J. S., Chow, E. K. C., Su, X., Varma, M., Alam, M. A. & Bashir, R., Apr 2011, In: Biomedical microdevices. 13, 2, p. 335-344 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Nanowires
  • High-k dielectric
  • Aluminum oxide
  • Gate dielectrics
  • Equipment and Supplies

• High-Resolution Projection Microstereolithography for Patterning of Neovasculature

  Raman, R., Bhaduri, B., Mir, M., Shkumatov, A., Lee, M. K., Popescu, G., Kong, H. & Bashir, R., Mar 9 2016, In: Advanced Healthcare Materials. 5, 5, p. 610-619 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Stereolithography
  • Tissue engineering
  • Assays
  • Immunosorbents
  • Tissue

• How far cardiac cells can see each other mechanically

  Tang, X., Bajaj, P., Bashir, R. & Saif, T. A., Jul 7 2011, In: Soft Matter. 7, 13, p. 6151-6158 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Substrates
  • cells
  • Stiffness
  • Continuum mechanics
  • Tissue

• Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines

  Cvetkovic, C., Ferrall-Fairbanks, M. C., Ko, E., Grant, L., Kong, H., Platt, M. O. & Bashir, R., Dec 1 2017, In: Scientific reports. 7, 1, 3775.

  Research output: Contribution to journal › Article › peer-review

  • Life Expectancy
  • Peptide Hydrolases
  • Skeletal Muscle
  • Tissue Engineering
  • Matrix Metalloproteinases

• Label-free imaging of cell attachment with photonic crystal enhanced microscopy

  Lidstone, E. A., Chaudhery, V., Kohl, A., Chan, V., Wolf-Jensen, T., Schook, L. B., Bashir, R. & Cunningham, B. T., Sep 21 2011, In: Analyst. 136, 18, p. 3608-3615 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Optics and Photonics
  • Photonic crystals
  • Microscopic examination
  • Labels
  • microscopy

• Label-free intracellular transport measured by spatial light interference microscopy

  Wang, Z., Millet, L., Chan, V., Ding, H., Gillette, M. U., Bashir, R. & Popescu, G., Feb 2011, In: Journal of biomedical optics. 16, 2, 026019.

  Research output: Contribution to journal › Article › peer-review

  • Light interference
  • organelles
  • Microscopic examination
  • Photobleaching
  • Labels

• Lipid bilayer coated Al₂O₃ nanopore sensors: Towards a hybrid biological solid-state nanopore

  Venkatesan, B. M., Polans, J., Comer, J., Sridhar, S., Wendell, D., Aksimentiev, A. & Bashir, R., Aug 1 2011, In: Biomedical microdevices. 13, 4, p. 671-682 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipid bilayers
  • Nanopores
  • Lipid Bilayers
  • Aluminum oxide
  • Sensors

• Magnetophoretic-based microfluidic device for DNA Concentration

  Shim, S., Shim, J., Taylor, W. R., Kosari, F., Vasmatzis, G., Ahlquist, D. A. & Bashir, R., Apr 1 2016, In: Biomedical microdevices. 18, 2, p. 1-8 8 p., 28.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Microfluidics
  • DNA
  • Nanofluidics
  • Nucleic acids

• Microfluidic differential immunocapture biochip for specific leukocyte counting

  Hassan, U., Watkins, N. N., Reddy, B., Damhorst, G. & Bashir, R., Apr 1 2016, In: Nature Protocols. 11, 4, p. 714-726 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Biochips
  • Biosensors
  • Microfluidics
  • Leukocytes
  • Biosensing Techniques

• Mobile Platform for Multiplexed Detection and Differentiation of Disease-Specific Nucleic Acid Sequences, Using Microfluidic Loop-Mediated Isothermal Amplification and Smartphone Detection

  Chen, W., Yu, H., Sun, F., Ornob, A., Brisbin, R., Ganguli, A., Vemuri, V., Strzebonski, P., Cui, G., Allen, K. J., Desai, S. A., Lin, W., Nash, D. M., Hirschberg, D. L., Brooks, I., Bashir, R. & Cunningham, B. T., Nov 7 2017, In: Analytical chemistry. 89, 21, p. 11219-11226 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Nucleic acid sequences
  • Pathogens
  • Microfluidics
  • Amplification
  • Smartphones

• Modeling and Analysis of Intercalant Effects on Circular DNA Conformation

  Krueger, E., Shim, J., Fathizadeh, A., Chang, A. N., Subei, B., Yocham, K. M., Davis, P. H., Graugnard, E., Khalili-Araghi, F., Bashir, R., Estrada, D. & Fologea, D., Sep 27 2016, In: ACS Nano. 10, 9, p. 8910-8917 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Circular DNA
  • Conformations
  • DNA
  • deoxyribonucleic acid
  • Nanopores

• Multivariate computational analysis of biosensor's data for improved CD64 quantification for sepsis diagnosis

  Hassan, U., Zhu, R. & Bashir, R., Apr 21 2018, In: Lab on a chip. 18, 8, p. 1231-1240 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Biosensing Techniques
  • Biosensors
  • Sepsis
  • Multivariate Analysis
  • Systemic Inflammatory Response Syndrome

• On a chip

  Watkins, N., Irimia, D., Toner, M. & Bashir, R., Nov 2011, In: IEEE Pulse. 2, 6, p. 19-27 9 p., 6088930.

  Research output: Contribution to journal › Article › peer-review

  • Emergency rooms
  • Ambulances
  • MEMS
  • Health

• On-chip electrical detection of parallel loop-mediated isothermal amplification with DG-BioFETs for the detection of foodborne bacterial pathogens

  Duarte-Guevara, C., Swaminathan, V. V., Reddy, B., Huang, J. C., Liu, Y. S. & Bashir, R., Jan 1 2016, In: RSC Advances. 6, 106, p. 103872-103887 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Pathogens
  • Amplification
  • Assays
  • Gold
  • Nucleic acids

• On-chip PMA labeling of foodborne pathogenic bacteria for viable qPCR and qLAMP detection

  Duarte-Guevara, P., Duarte-Guevara, C., Ornob, A. & Bashir, R., Aug 1 2016, In: Microfluidics and Nanofluidics. 20, 8, 114.

  Research output: Contribution to journal › Article › peer-review

  • propidium monoazide
  • Bacteria
  • bacteria
  • marking
  • Labeling

• Optical measurement of cycle-dependent cell growth

  Mir, M., Wang, Z., Shen, Z., Bednarz, M., Bashir, R., Golding, I., Prasanth, S. G. & Popescu, G., Aug 9 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 32, p. 13124-13129 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Cycle
  • Growth
  • Interference Microscopy
  • Cell Size
  • Microscopy

• Optogenetic skeletal muscle-powered adaptive biological machines

  Raman, R., Cvetkovic, C., Uzel, S. G. M., Platt, R. J., Sengupta, P., Kamm, R. D. & Bashir, R., Mar 29 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 13, p. 3497-3502 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Optogenetics
  • Bioengineering
  • Skeleton
  • Locomotion
  • Skeletal Muscle

• Optomechanical microrheology of single adherent cancer cells

  Adeniba, O. O., Corbin, E. A., Ewoldt, R. H. & Bashir, R., Mar 1 2018, In: APL Bioengineering. 2, 1, 016108.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cells
  • Viscoelastic Substances
  • Cell membranes
  • Soft materials
  • Mechanical properties

• Pattern analysis and spatial distribution of neurons in culture

  Millet, L. J., Collens, M. B., Perry, G. L. W. & Bashir, R., Dec 1 2011, In: Integrative Biology. 3, 12, p. 1167-1178 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Spatial Analysis
  • Spatial distribution
  • Neurons
  • Neurology
  • Dendrites (metallography)

• Patterning the differentiation of C2C12 skeletal myoblasts

  Bajaj, P., Reddy, B., Millet, L., Wei, C., Zorlutuna, P., Bao, G. & Bashir, R., Sep 1 2011, In: Integrative Biology. 3, 9, p. 897-909 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Skeletal Myoblasts
  • Fusion reactions
  • Substrates
  • Cells
  • Muscle

• Perspective: The promise of multi-cellular engineered living systems

  Kamm, R. D., Bashir, R., Arora, N., Dar, R. D., Gillette, M. U., Griffith, L. G., Kemp, M. L., Kinlaw, K., Levin, M., Martin, A. C., McDevitt, T. C., Nerem, R. M., Powers, M. J., Saif, T. A., Sharpe, J., Takayama, S., Takeuchi, S., Weiss, R., Ye, K., Yevick, H. G. & 1 others, Zaman, M. H., Dec 1 2018, In: APL Bioengineering. 2, 4, 040901.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bioprinting
  • Cytology
  • Stem cells
  • Organoids
  • Assays

• Pixelated spatial gene expression analysis from tissue

  Ganguli, A., Ornob, A., Spegazzini, N., Liu, Y., Damhorst, G., Ghonge, T., Thornton, B., Konopka, C. J., Dobrucki, W., Clare, S. E., Bhargava, R., Smith, A. M., Kosari, F. & Bashir, R., Dec 1 2018, In: Nature communications. 9, 1, 202.

  Research output: Contribution to journal › Article › peer-review

  • gene expression
  • Gene expression
  • Tissue
  • ribonucleic acids
  • Amplification

• Robust label-free microRNA detection using one million ISFET array

  Ganguli, A., Watanabe, Y., Hwang, M. T., Huang, J. C. & Bashir, R., Jun 2 2018, In: Biomedical microdevices. 20, 2, 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Ion sensitive field effect transistors
  • Nucleic acids
  • Assays
  • Nucleic Acids
  • Molecules

• Separating beads and cells in multi-channel microfluidic devices using dielectrophoresis and laminar flow

  Millet, L. J., Park, K., Watkins, N. N., Jimmy Hsia, K. & Bashir, R., Feb 2011, In: Journal of Visualized Experiments. 48, e2545.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Electrophoresis
  • Microfluidics
  • Laminar flow
  • Fluidics

• Silicon field effect transistors as dual-use sensor-heater hybrids

  Reddy, B., Elibol, O. H., Nair, P. R., Dorvel, B. R., Butler, F., Ahsan, Z., Bergstrom, D. E., Alam, M. A. & Bashir, R., Feb 1 2011, In: Analytical Chemistry. 83, 3, p. 888-895 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Silicon
  • Field effect transistors
  • Transistors
  • Dielectric heating
  • Sensors

• Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

  Pagan-Diaz, G. J., Zhang, X., Grant, L., Kim, Y., Aydin, O., Cvetkovic, C., Ko, E., Solomon, E., Hollis, J., Kong, H., Saif, T., Gazzola, M. & Bashir, R., Jun 6 2018, In: Advanced Functional Materials. 28, 23, 1801145.

  Research output: Contribution to journal › Article › peer-review

  • walking machines
  • Scaffolds
  • Tissue
  • Robotics
  • Actuators

• Stereolithography-based hydrogel microenvironments to examine cellular interactions

  Zorlutuna, P., Jeong, J. H., Kong, H. & Bashir, R., Oct 7 2011, In: Advanced Functional Materials. 21, 19, p. 3642-3651 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Stereolithography
  • Hydrogels
  • Polyethylene Glycol Dimethacrylate Hydrogel
  • Neurons
  • Choline